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US Patent 11,596,592 B2.
March 11, 2023
By: Christine Esposito
US Patent 11,596,592 B2 (Jun-Seok Yeom, Woo-Sun Shim, Young-Min Hwang, Seung-Min Yoo, Seol-Hoon Lee, Nae-Gyu Kang); LG Housheold & Health Care, Seoul, Korea, has patented a soluble microneedle for delivering filler particles into skin. It comprises a material forming a soluble microneedle that has a mixture of oligo hyaluronic acid, sodium carboxymethyl cellulose (Na-CMC) and a plasticizer; and a plurality of filler particles comprising crosslinked hyaluronic acid and trehalose. The filler particles, which are impregnated in the material forming the soluble microneedle, are adapted to be delivered when the material dissolves after the microneedle is applied into skin. The crosslinked hyaluronic acid in the filler particles swell after intradermal or subcutaneous delivery.
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